my account
Login
  Loading... Please wait...

Product Details

SC-514 | IKK-2 inhibitor

SC-514 (354812-17-2) is a reversible, competitive inhibitor of IKK2 (IC50 = 11.2 μM). Has not been demonstrated to inhibit other IKK isoforms, or other kinases. SC-514 displays dose-dependent inhibition of the transcription of NF-κB dependent genes in cell culture1.

References/Citations
1) Kishore et al. (2003), A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts; J. Biol. Chem., 278 32861

swipe
SC-514 | 354812-17-2 | Structure | Supplier

Catalog#  10-1054

$65.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
354812-17-2
Catalog Number:
10-1054
Activity:
IKK-2 inhibitor
Chemical Name:
5-(Thien-3-yl)-3-aminothiophene-2-carboxamide
Molecular Weight:
224.3
Molecular Formula:
C9H8N2OS2
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
Yellow solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the SC-514 | IKK-2 inhibitor to your wish list.