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Product Details

SGC707 | PRMT3 inhibitor

SGC707 (1687736-54-4) is a potent (IC50 = 31 nM) and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).1  Selective against 31 other methyltransferases. An extremely useful probe for investigating the role of PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.

References/Citations

1) Kaniskan et al. (2015), A potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3); Angew. Chem. Int. Ed. Engl., 54 5166

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Focus Biomolecules cell signaling reagent supplier, chemical structure of SGC707 | PRMT3 inhibitor | CAS 1687736-54-4

Catalog#  10-1610-0005

$65.00
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Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
1687736-54-4
Catalog Number:
10-1610
Activity:
PRMT3 inhibitor
Chemical Name:
1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
Molecular Weight:
298.34
Molecular Formula:
C16H18N4O2
Solubility:
Soluble in DMSO (up to XX mg/ml)
Physical Properties:
Beige solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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