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  • GSK-J4 | JMJ H3K27 Demethylase inhibitor (Cell Permeable)

    CAS:
    1373423-53-0
    Catalog Number:
    10-1394
    Activity:
    JMJ H3K27 Demethylase inhibitor (Cell Permeable)
    Chemical Name:
    N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
    Molecular Weight:
    417.48
    Molecular Formula:
    C24H27N5O2
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 40 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GSK126 | EZH2 methyltransferase inhibitor

    CAS:
    1346574-57-9
    Catalog Number:
    10-3394
    Activity:
    EZH2 methyltransferase inhibitor
    Chemical Names:
    N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide
    Molecular Weight:
    526.69
    Molecular Formula:
    C31H38N6O2
    Solubility:
    Soluble in DMSO (16 mg/ml)
    Physical Properties:
    Cream solid
    Purity:
    >98% HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GSK1702934A | TRPC 3/6 activator

    Catalog Number:
    10-1445
    CAS:
    924377-85-5
    Activity:
    TRPC3/6 activator
    Chemical Name:
    1-(1-(5,6,7,8-Tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl)-1H-benzo[d]- imidazole-2(3H)-one
    Molecular Weight:
    395.52
    Molecular Formula:
    C22H25N3O2S
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $110.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GSK2334470 | Potent and selective PDK1 inhibitor

    CAS:
    1227911-45-6
    Catalog Number:
    10-4725
    Activity:
    Potent and selective PDK1 inhibitor
    Chemical Name:
    (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide
    Molecular Weight:
    462.60
    Molecular Formula:
    C25H34N8O
    Solubility:
    Soluble in DMSO (> 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $59.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GSK2606414 | PERK inhibitor

    CAS:
    1337531-36-8
    Catalog Number:
    10-4716
    View Product This product has multiple variants. The options may be chosen on the product page
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