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  • Selinexor | Inhibitor of the nuclear export receptor CRM1/XPO1

    CAS:
    1393477-72-9
    Catalog Number:
    10-4011
    Activity:
    Inhibitor of the nuclear export receptor CRM1/XPO1
    Chemical Name:
    (Z)-3-[3-[3,5-Bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N’-pyrazin-2-ylprop-2-enehydrazide
    Alternate Name:
    KPT-330
    Molecular Weight:
    443.31
    Molecular Formula:
    C17H11F6N7O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml). or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Selonsertib | ASK1 inhibitor

    CAS:
    1448428-04-3
    Catalog Number:
    10-4696
    Activity:
    ASK1 inhibitor
    Chemical Names:
    5-(4-Cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl)-1,2,4-triazol-3-yl)pyridine-2-yl]benzamide
    Alternate Name:
    GS-4997
    Molecular Weight:
    445.50
    Molecular Formula:
    C24H24FN7O
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Selpercatinib | Potent and selective RET kinase inhibitor

    CAS:
    2152628-33-4
    Catalog Number:
    10-4407
    View Product This product has multiple variants. The options may be chosen on the product page
  • Seriniquinone | Autophagy inducer

    Catalog Number:
    10-1608
    CAS #:
    22200-69-7
    Activity:
    Autophagy inducer
    Chemical Name:
    Dinaphthol[2,3-b:2’,3’-d]thiophene-5,7,12,13-tetraone
    Molecular Weight:
    344.34
    Molecular Formula:
    C20H8O4S
    Solubility:
    Soluble in DMSO (up to 15 mg/ml with warming) or in DMF (up to 15 mg/ml)
    Physical Properties:
    Orange solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Serodolin | ß-Arrestin-biased 5-HT7 antagonist

    CAS:
    1814929-81-1
    Catalog Number:
    10-4086
    Activity:
    ß-Arrestin-biased 5-HT7 antagonist
    Chemical Names:
    1-(5-(4-(4-Fluorophenyl)piperazin-1-yl)pentyl)-1H-benzo[d]imidazole-2(3H)-one
    Molecular Weight:
    382.47
    Molecular Formula:
    C22H27FN4O
    Solubility:
    Soluble in DMSO (at least 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
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