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Spermine NONOate | NO Donor

Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.    The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1    Dissociation is essentially instantaneous at a pH of 5.0.   

References/Citations

1) Keefer et al. (1996), “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol., 268 281

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Catalog#  10-4549-0010

$30.00
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CAS:
136587-13-8
Catalog Number:
10-4549
Activity:
NO Donor
Chemical Name:
1-{N-[3-Aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino}-diazen-1-ium-1,2-diolate
Molecular Weight:
262.35
Molecular Formula:
C10H26N6O2
Solubility:
Soluble in Water or Ethanol
Physical Properties:
Off-white solid
Purity:
97% by (1H-NMR)
Storage Temperature:
-80°C (des.)
Stability:
Stable for 1 year as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use.
Shipping Code:
Dry Ice
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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