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Sphingosine-1-phosphate | EDG receptor ligand

Sphingosine-1-phosphate (26993-30-6) is an endogenous sphingolipid metabolite known to be involved in many cellular responses including angiogenesis, vascular maturation, cardiac development and immunity. These effects are mediated through a family of 5 G-protein-coupled receptors.1,2,3

References/Citations
1) Spiegel and Milstien (2003) Sphingosine-1-phosphate: an enigmatic signaling lipid; Nat. Rev. Mol. Cell Biol., 4 397
2) Rosen et al. (2009) Sphingosine-1-phosphate receptor signaling; Annu. Rev .Biochem., 78 743
3) Maceyka et al. (2012) Sphingosine-1-phosphate signaling and its role in disease; Trends Cell Biol., 22 50

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Catalog#  10-4526

$65.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
26993-30-6
Catalog Number:
10-4526
Activity:
EDG receptor ligand
Chemical Name:
Sphingosine-1-phosphate, D-erythro
Molecular Weight:
379.47
Molecular Formula:
C18H38NO5P
Solubility:
Soluble in anhydrous methanol (up to 0.5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Solutions in methanol or in BSA/water may be stored at -20° for up to 2 months. Precipitate may form upon thawng, but will redissolve with warming.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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