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Product Details

SR-3576 | JNK3 inhibitor

SR-3576 (1164153-22-3) is a potent and selective JNK3 inhibitor. IC50 = 7nM and >2800-fold selective over p38.1 Cell permeable.

References/Citations

1) Kamenecka et al. (2009), Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38; J. Biol. Chem., 284 12853

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Focus Biomolecules cell signaling reagent supplier, chemical structure of SR-3576 | JNK3 inhibitor | CAS 1164153-22-3

Catalog#  10-1498-0005

$100.00
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Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
1164153-22-3
Catalog Number:
10-1498
Activity:
JNK3 inhibitor
Chemical Name:
3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
Molecular Weight:
501.53
Molecular Formula:
C27H27N5O5
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml with warming)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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