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Product Details

SR1 | Maintains stem cells in pluripotent state

SR1 (1227633-49-9) extends the pluripotency of hematopoietic stem cells (IC50 = 127 nM) by antagonizing AhR signaling resulting in continued expression of CD34. Effects are easily reversed by the removal of the SR1.

References/Citations
1) Boitano et al. (2010), Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells; Science, 329 1354

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Catalog#  10-4508

$38.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
1227633-49-9
Catalog Number:
10-4508
Activity:
Maintains stem cells in pluripotent state
Molecular Weight:
466
Molecular Formula:
C24H23N5OS
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Off-white solid
Purity:
99% by HPLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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