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Product Details

Src-I1 | Src kinase inhibitor

Src-I1 (179248-59-0) is a potent and competitive dual site (ATP- and peptide-binding) Src kinase inhibitor (IC50's = 44 nM for Src and 88 nM for Lck). Src-I1 also inhibits VEGFR2 (IC50 = 320 nM).

References/Citations
1) Tian et al. (2001) Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines; Biochem. 40 7084
2) Bain et al. (2007) The selectivity of protein kinase inhibitors: a further update; Biochem. J. 408 297

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SRC-I1 | 179248-59-0 | Structure | Supplier

Catalog#  10-1020

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
179248-59-0
Catalog Number:
10-1020
Activity:
Src kinase inhibitor
Chemical Name:
6,7-Dimethoxy-N-(4-Phenoxyphenyl)-4-quinazolinamine
Molecular Weight:
373.41
Molecular Formula:
C22H19N3O3
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
White or off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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