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Product Details
Stauprimide | Primes stem cells for differentiation
Stauprimide (154589-96-5) dramatically primes embryonic stem cells for differentiation. Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby downregulating c-Myc.3
References/Citations
1) Zhu et al. (2009), A small molecule primes embryonic stem cells for differentiation; Cell Stem Cell, 4 416
2) Zaret et al. (2009), Using small molecules to great effect in stem cell differentiation; Cell Stem Cell, 4 373
3) Bouvard et al. (2017) Small molecule selectively suppresses MYC transcription in cancer cells; Proc. Natl. Acad. SCi. USA 114 3497
Catalog# 10-1189
$85.00
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
CAS:
154589-96-5
Catalog Number:
10-1189
Activity:
Primes stem cells for differentiation
Chemical Name:
N-Benzoyl-7-oxostaurosporine
Molecular Weight:
584.64
Molecular Formula:
C35H28N4O5
Solubility:
Soluble in DMSO (up to 20 mg/ml). Very slightly soluble in Ethanol.
Physical Properties:
Orange solid
Purity:
98% by TLC
NMR (Conforms)
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.
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