STING Degrader 2 | STING molecular glue
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $120.00 | ||
| 25 mg | $425.00 |
STING Degrader 2 is a molecular glue that covalently binds both STING and RNF126 E3 ligase leading to proteasomal degradation. It displayed sustained STING degradation with faster onset and at lower concentration (3 µM) when compared to the STING PROTAC SP23.
References/Citations:
- Nakamura et al. (2024), Development of STING Degrader with double covalent ligands; Bioorg. Med. Chem. Lett. 102 129677
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
STING Degrader 2 is a molecular glue that covalently binds both STING and RNF126 E3 ligase leading to proteasomal degradation. It displayed sustained STING degradation with faster onset and at lower concentration (3 µM) when compared to the STING PROTAC SP23.
References/Citations:
- Nakamura et al. (2024), Development of STING Degrader with double covalent ligands; Bioorg. Med. Chem. Lett. 102 129677
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