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Product Details

SU-1498 | VEGFR kinase inhibitor

SU-1498 (168835-82-3) is a potent, reversible, selective inhibitor of VEGFR-2, also known as Flk-1 (IC50 = 700 nM). Inhibition of VEGFR-2 blocks angiogenesis in both in vitro and in vivo models. Cell permeable.

References/Citations
1) Cho et al. (2005), Retinoic acid and erythropoietin maintain alveolar development in mice treated with an angiogenesis inhibitor; Am. J. Respir. Cell Mol. Biol., 33 622
2) Wang et al. (2002), Interplay between integrins and FLK-1 in shear stress-induced signaling; Am. J. Physiol. Cell Physiol., 283 C1540
3) Strawn et al. (1996), FLK-1 as a target for tumor growth inhibition; Cancer Res., 56 3540

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Catalog#  10-2074

$55.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
168835-82-3
Catalog Number:
10-2074
Activity:
VEGFR kinase inhibitor
Chemical Name:
(E)-N-(3'-Phenylpropyl)-α-cyano-3',5'-diisopropyl-4'-hydroxycinnamamide
Molecular Weight:
390.52
Molecular Formula:
C25H30N2O2
Solubility:
Soluble in DMSO.
Physical Properties:
Pale yellow solid
Purity:
98%
Storage Temperature:
-20°
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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