February 13, 2026

Maraviroc as glioblastoma treatment

FOCUS on Drug Repurposing. A study just published in Neuron suggests the HIV drug Maraviroc (a CCR5 antagonist) may be useful for the treatment of glioblastoma […]
September 18, 2025

Possible strategy for neuroblastoma

FOCUS on Neuroblastoma. In a paper just out in Nature Communications, Singh et al. report: “To better understand the cellular plasticity of neuroblastoma in chemoresistance, we […]
February 22, 2024

GBR-12909 suppresses cancer stem cell functions

Journal Club: In the February issue of Nature Cancer, CJ Bergin and coworkers from the University of Ottawa demonstrated that vanoxerine (GBR-12909), a well-known dopamine transporter […]
March 23, 2023

Cyclopamine analog for cancer stem cells

Focus on Drug Discovery: Saridegib is a natural product-inspired drug candidate. Its prototype, cyclopamine was discovered as a teratogenic steroidal alkaloid that was found to cause […]