FOCUS on Drug Repurposing. A study just published in Neuron suggests the HIV drug Maraviroc (a CCR5 antagonist) may be useful for the treatment of glioblastoma […]
FOCUS on Neuroblastoma. In a paper just out in Nature Communications, Singh et al. report: “To better understand the cellular plasticity of neuroblastoma in chemoresistance, we […]
Journal Club: In the February issue of Nature Cancer, CJ Bergin and coworkers from the University of Ottawa demonstrated that vanoxerine (GBR-12909), a well-known dopamine transporter […]
Focus on Drug Discovery: Saridegib is a natural product-inspired drug candidate. Its prototype, cyclopamine was discovered as a teratogenic steroidal alkaloid that was found to cause […]
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