TCID | DUB inhibitor

CAS:
30675-13-9
Catalog Number:
10-2428
Activity:
DUB inhibitor
Chemical Name:
4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione
Molecular Weight:
283.93
Molecular Formula:
C9H2Cl4O2
Solubility:
Soluble in DMSO (up to 25 mg/ml),
Physical Properties:
White solid
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Available Options

Size :PriceQuantity 
10 mg$80.00
50 mg$320.00

TCID (30675-13-9) inhibits ubiquitin C-terminal hydrolase L3 (UCH-L3). IC50=0.6 μM, 125-fold selective over UCH-L1, IC50=75 μM. Cell permeable.

References/Citations:

1) Love et al. (2007), Mechanisms, biology and inhibitors of deubiquitinating enzymes; Nat. Chem. Biol., 3 697
2) Mtango et al. (2012), Essential role of ubiquitin C-terminal hydrolases UCHL1 and UCHL3 in mammalian oocyte maturation; J. Cell Physiol., 227 2022

CAS:
30675-13-9
Catalog Number:
10-2428
Activity:
DUB inhibitor
Chemical Name:
4,5,6,7-Tetrachloro-1H-indene-1,3(2H)-dione
Molecular Weight:
283.93
Molecular Formula:
C9H2Cl4O2
Solubility:
Soluble in DMSO (up to 25 mg/ml),
Physical Properties:
White solid
Purity:
97% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee

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