TRIM-473 | RING ligase TRIM58 ligand
Available Options
| Size: | Price | Quantity | |
|---|---|---|---|
| 5 mg | $85.00 | ||
| 25 mg | $295.00 |
TRIM-473 is a ligand (EC50 = 5.3 µM) for the PRY-SPRY domain of the RING ligase TRIM58. An interesting new tool for the development of heterobifunctional degraders of this novel tissue-selective (erythroid precursor cells) ligase.
References/Citations:
- Hoegenauer et al. (2023), Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase; ACS Med. Chem. Lett., 14 1631
C25H34N6
>98% by HPLC
NMR: (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
TRIM-473 is a ligand (EC50 = 5.3 µM) for the PRY-SPRY domain of the RING ligase TRIM58. An interesting new tool for the development of heterobifunctional degraders of this novel tissue-selective (erythroid precursor cells) ligase.
References/Citations:
- Hoegenauer et al. (2023), Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase; ACS Med. Chem. Lett., 14 1631
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