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Product Details

TRIM | Nitric oxide synthase inhibitor

TRIM (25371-96-4) is a potent inhibitor of neuronal and inducible nitric oxide synthases, (IC50 = 28.2 and 27.0 μM respectively). Inhibits endothelial NOS with lower potency (IC50 = 1057.5 μM1. TRIM displays antinociceptive activity in vivo2.

References/Citations
1) Handy et al. (1995), The antinociceptive effect of 1-(2-trifluoromethylphenyl)imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse; Br. J. Pharmacol., 116 2349
2) Handy et al. (1996), Inhibition of nitric oxide synthase by 1-(2-trifluoromethylphenyl) imidazole (TRIM) in vitro: antinociceptive and cardiovascular effects; Br. J. Pharmacol., 119 423

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Catalog#  10-2699

$35.00
Quantity
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CAS:
25371-96-4
Catalog Number:
10-2699
Activity:
Nitric oxide synthase inhibitor
Chemical Name:
1-(2-Trifluoromethylphenyl)imidazole
Molecular Weight:
212.18
Molecular Formula:
C107F3N2
Solubility:
Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 20 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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