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Product Details

Ursolic Acid | Angiogenesis inhibitor

Ursolic acid (77-52-1) inhibits endothelial cell proliferation and migration (IC50=5 µM) and angiogenesis.1 Promotes skeletal muscle rejuvenation via enhanced SIRT1 expression.2 Induces apoptosis in malignant mesothelioma cells.3

References/Citations

1) Sohn et al. (1995), Anti-angiogenic activity of triterpene acids; Cancer Lett., 94 213
2) Bakhtiari et al. (2016), Short-term ursolic acid promotes skeletal muscle rejuvenation through enhancing of SIRT1 expression and satellite cells proliferation; Biomed. Pharmacother., 78 185
3) Sohn et al. (2016), Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell; J. Biol. Sci., 12 1279

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Catalog#  10-4010-0050

$40.00
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Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
77-52-1
Catalog Number:
10-4010
Activity:
Angiogenesis inhibitor
Chemical Name:
3β-Hydroxyurs-12-en-28-oic acid
Molecular Weight:
456.70
Molecular Formula:
C30H48O3
Solubility:
Soluble in DMSO (up to 25 mg/ml with warming)
Physical Properties:
White solid
Purity:
>95% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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