my account
Login
  Loading... Please wait...

Product Details

Zafirlukast | HSP70 inhibitor and leukotriene antagonist

Zafirlukast (107753-78-6) is a competitive and selective leukotriene receptor antagonist1. Also inhibits calcium ionophore induced production of leukotriene B4 and leukotriene C4, which suggests a potential 5-LO inhibitory activity2. Cell permeable and orally active.

References/Citations
1) Adkins and Brogden, (1998), Zafirlukast. A review of its pharmacology and therapeutic potential in the management of asthma; Drugs, 55 121
2) Woszczek et al., (2010), Concentration-dependent noncysteinyl leukotriene type 1 receptor-mediated inhibitory activity of leukotriene receptor antagonists; J. Immunol. 184 2218
3) Wyttenbach & Kuentz (2017), Glass-forming ability of compounds in marketed amorphous drug products; Eur. J. Pharm. and Biopharm., 112 204 [Focus Citation]

swipe
Focus Biomolecules offers cell signaling reagent, Zafirlukast | HSP70 inhibitor, leukotriene antagonist | CAS 107753-78-6

Catalog#  10-1100

$28.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
107753-78-6
Catalog Number:
10-1100
Activity:
Hsp70 inhibitor
Alternate Names:
ICI-204219
Molecular Weight:
575.69
Molecular Formula:
C31H33N3O6S
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
White or pink solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 2 years as supplied. Protect from exposure to moisture. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the Zafirlukast | HSP70 inhibitor and leukotriene antagonist to your wish list.