Modify Search
Select all
Products
Pages
Posts
Modify Search
Select all
Products
Pages
Posts

ZM-306416 | VEGFR kinase inhibitor

CAS:
196603-47-1
Catalog Number:
10-1019
Activity:
VEGFR kinase inhibitor
Chemical Name:
4-[(4′-Chloro-2′-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride
Molecular Weight:
370.12
Molecular Formula:
C16H13ClFN3O2·HCl
Solubility:
Soluble in DMSO (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

ZM-306416 (196603-47-1) is a VEGF receptor tyrosine kinase inhibitor with selectivity over FGFR-1 (KDR IC50 = 100 nM; FLT IC50 = 2 μM).

References/Citations:

1) Hennequin et al. (1999) Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors. J. Med. Chem. 42 5369

ZM-306416 | VEGFR kinase inhibitor is also available in the Cellular Metabolism Library.
CAS:
196603-47-1
Catalog Number:
10-1019
Activity:
VEGFR kinase inhibitor
Chemical Name:
4-[(4′-Chloro-2′-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride
Molecular Weight:
370.12
Molecular Formula:
C16H13ClFN3O2·HCl
Solubility:
Soluble in DMSO (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

Add to Quote

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee