Approved Drugs
Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).
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5-Azacytidine | DNA hypomethylation agent
From $20.00CAS:320-67-2Catalog Number:10-1267Activity:DNA hypomethylation agentAlternate Names:Ladakamycin; U-18496; NSC-102816; AzaCChemical Name:4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-oneMolecular Weight:244.21Molecular Formula:C8H12N4O5Solubility:Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
5-Fluorouracil | Inhibitor of thymidylate synthase
From $20.00CAS:51-21-8Catalog Number:10-1276Activity:Inhibitor of thymidylate synthaseAlternate Names:5-FUChemical Name:5-Fluoro-1H,3H-pyrimidine-2,4-dioneMolecular Weight:130.08Molecular Formula:C4H3FN2O2Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:White solidPurity:98%Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
5-Fluorouridine | Proapoptotic antiproliferative agent
From $60.00CAS:316-46-1Catalog Number:10-1277Activity:Proapoptotic antiproliferative agentChemical Name:1-(β-D-Ribofuranosyl)-5-fluorouracilAlternate Names:FUrdMolecular Weight:262.19Molecular Formula:C9H11FN2O6Solubility:Soluble in DMSO (up to 50 mg/ml), in Water (up to 50 mg/ml), or in Ethanol (up to 6 mg/ml with warming)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
6-Mercaptopurine | Purine antimetabolite and immunomodulator
From $25.00CAS:6112-76-1Catalog Number:10-4698Activity:Purine antimetabolite and immunomodulatorChemical Names:3,7-Dihydropurine-6-thione monohydrateAlternate Name:6-MPMolecular Weight:170.19Molecular Formula:C5H4N4S·H2OSolubility:Soluble in DMSO (>50 mg/ml); ethanol (5 mg/ml with warming)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
6-Thioguanine | Anticancer agent / Downregulates DNMT1
From $30.00CAS:154-42-7Catalog Number:10-1282Activity:Anticancer agent / Downregulates DNMT1Chemical Name:2-Amino-6-mercaptopurineAlternate Names:6-TG; NSC 752, NSC 76504Molecular Weight:167.19Molecular Formula:C5H5N5SSolubility:Soluble in DMF (up to 1.5 mg/ml with warming)Physical Properties:Pale yellow solidPurity:96% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.Shipping Code:RT -
9-Hydroxyrisperidone | Risperidone metabolite
From $30.00CAS:144598-75-4Catalog Number:10-2300Activity:Risperidone metaboliteChemical Name:3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-oneAlternate Name:PaliperidoneMolecular Weight:426.48Molecular Formula:C23H27FN4O3Solubility:Soluble in DMSO (up to 4 mg/ml).Physical Properties:White solidPurity:95% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT
