Approved Drugs

Drugs approved by the FDA or other agencies for use in medicine are excellent tools for research because they are demonstrated to have good absorption (bioavailable), distribution and activity, and pharmacokinetics for use in vivo experiments. They are used in cells or animals for basic research, and for drug discovery (repurposing, benchmarking and other applications).

  • Bedaquiline | Antituberculosis agent/bacterial ATP synthase inhibitor

    CAS:
    843663-66-1
    Catalog Number:
    10-4403
    Activity:
    Antituberculosis agent/Bacterial ATP synthase inhibitor
    Chemical Names:
    (1R,2S)-1-(6-Bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-naphthalen-1-yl-1-phenylbutan-2-o
    Alternate Name:
    TMC207; R207910
    Molecular Weight:
    555.50
    Molecular Formula:
    C32H31BrN2O2
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% HPLC
    NMR (Conforms)
    Storage Temperature:
    Room temperature
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Bempedoic acid | ATP citrate lyase inhibitor

    CAS:
    738606-46-7
    Catalog Number:
    10-4114
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  • Bepridil | Calcium channel blocker\Active against SARS-CoV2

    CAS:
    74764-40-2
    Catalog Number:
    10-4958
    Activity:
    Calcium channel blocker/anti-SARS-CoV2
    Chemical Name:
    N-Benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline hydrochloride
    Molecular Weight:
    403.00
    Molecular Formula:
    C24H34N2O·HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or ethanol (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Bexarotene | Retinoid RXR agonist

    CAS:
    153559-49-0
    Catalog Number:
    10-2121
    Activity:
    Retinoid RXR agonist
    Alternate Names:
    LGD-1069, SR-11247
    Chemical Name:
    4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
    Molecular Weight:
    348.49
    Molecular Formula:
    C24H28O2
    Solubility:
    Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 10 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $40.00
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  • Binimetinib | MEK1/2 inhibitor

    CAS:
    606143-89-9
    Catalog Number:
    10-4789
    Activity:
    MEK1/2 inhibitor
    Chemical Name:
    6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
    Alternate Names:
    ARRY-162; MEK162
    Molecular Weight:
    441.23
    Molecular Formula:
    C17H15BrF2N4O3
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $39.00
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  • Bleomycin sulfate | Induces double strand DNA breaks

    CAS:
    9041-93-4
    Catalog Number:
    10-2623
    Activity:
    Fibrosis-inducing agent
    Source:
    From Streptomyces verticillus
    Molecular Weight:
    1512.62
    Molecular Formula:
    C55H85N17O25S4
    Solubility:
    Soluble in Water (up to 20 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    Contains a mixture of A2 (~70%) and B2 (~30%) forms
    95% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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