Natural products
‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).
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Thapsigargin | SERCA inhibitor
From $60.00CAS:67526-95-8Catalog Number:10-2105Activity:SERCA inhibitorChemical Name:Isolated from Thapsia garganicaMolecular Weight:650.77Molecular Formula:C34H50O12Solubility:Soluble in DMSO (up to 65 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:Colorless waxy solid / filmPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.Shipping Code:RT -
Thiostrepton | Antibiotic and FOXM1 inhibitor
From $85.00CAS:1393-48-2Catalog Number:10-2108Activity:Antibiotic and FOXM1 inhibitorChemical Name:Fermentation product from Streptomyces azureusMolecular Weight:1664.91Molecular Formula:C72H85N19O185Solubility:Soluble in DMSO (up to 15 mg/ml), or in Chloroform (up to 5 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC and HPLCStorage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.Shipping Code:RT -
Tomentosin | Inhibits NFkB activation
From $75.00CAS:33649-15-9Catalog Number:10-3538Activity:Inhibits NFkB activationAlternate Names:XanthalonginChemical Name:Sesquiterpenoid isolated from Inula viscosaMolecular Weight:248.32Molecular Formula:C15H20O3Solubility:Soluble in DMSO (50 mg/ml)Physical Properties:Yellow oilPurity:97% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 month.Shipping Code:RT -
Toyocamycin | Unfolded protein response (UPR) inhibitor
From $70.00CAS:606-58-6Catalog Number:10-2750Activity:Unfolded protein response (UPR) inhibitorChemical Name:4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrileAlternate Names:7-Deaza-7-cyanoadenosine; NSC 63701; NSC 99843; Neuro 000027; Unamycin B; VengicideMolecular Weight:291.26Molecular Formula:C12H13N5O4Solubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White or off-white solidPurity:97% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Triacsin C | Acyl-CoA synthase inhibitor
From $90.00CAS:76896-80-5Catalog Number:10-2109Activity:Acyl-CoA synthase inhibitorChemical Name:(3E)-1-Hydroxy-3-((2E,4Z,7E)-undeca-2,4,7-triene-1-ylidene)triaz-1-eneMolecular Weight:207.28Molecular Formula:C11H17N3OSolubility:Supplied in solution in DMSO at a concentration of 1 mg/ml. Maximum solubility in DMSO is 25 mg/ml.Physical Properties:Solution in DMSOPurity:95% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions further diluted with DMSO may be stored at -20° for up to 2 months.Shipping Code:Blue Ice -
Trichostatin A | HDAC inhibitor
From $78.00CAS:58880-19-6Catalog Number:10-2110Activity:HDAC inhibitorAlternate Names:TSAChemical Name:(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamideMolecular Weight:302.38Molecular Formula:C17H22N2O3Solubility:Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 3 mg/ml).Physical Properties:Tan solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
