PhysioProcesses

Natural products

‘Natural products’ are a fascinating and diverse group of bioactive molecules that are produced by living organisms. These types of compounds are typically divided into two classes: primary metabolites, used for intrinsic function of the producing organism and secondary metabolites, used to increase the competitiveness of the organism within its environment. Both classes of natural products have many potential uses, including drugs (e.g. antibiotics, analgesics, cancer drugs, many others), building blocks for other molecules, and chemical tools/probes (e.g. fluorescence, luminescence).

  • Visnagin| Protects against doxorubicin-induced cardiomyopathy

    CAS:
    82-57-5
    Catalog Number:
    10-4614
    Activity:
    Protects against doxorubicin-induced cardiomyopathy
    Chemical Name:
    4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one
    Source:
    Isolated from Ammi visnaga
    Molecular Weight:
    230.22
    Molecular Formula:
    C13H10O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $35.00
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  • Withaferin A | NFkB and angiogenesis inhibitor

    CAS:
    5119-48-2
    Catalog Number:
    10-2114
    Activity:
    NFκB and angiogenesis inhibitor
    Chemical Name:
    (4β, 5β, 6β, 22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone
    Molecular Weight:
    470.60
    Molecular Formula:
    C28H38O6
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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  • Wortmannin | PI3K inhibitor

    CAS:
    19545-26-7
    Catalog Number:
    10-2115
    Activity:
    PI3K inhibitor
    Chemical Name:
    [(1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-2(10),12(19),14-trien-3-yl] acetate
    Molecular Weight:
    428.44
    Molecular Formula:
    C23H24O8
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Dried aliquots evaporated from ethanol may be stored at -20° for several months. Solutions however are not stable and must be used within one working day. Note: Wortmannin decomposes fairly quickly in culture media
    Shipping Code:
    RT
    From $42.00
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  • Xanthohumol | VCP inhibitor / Autophagy inhibitor

    CAS:
    6754-58-1
    Catalog Number:
    10-1188
    Activity:
    VCP inhibitor / Autophagy inhibitor
    Molecular Weight:
    354.41
    Molecular Formula:
    C21H22O5
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $75.00
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  • YM-254890 | Gq inhibitor

    CAS:
    568580-02-9
    Catalog Number:
    10-1590
    Activity:
    Gq inhibitor
    Source:
    Isolated from Chromobacterium sp.
    Molecular Weight:
    960.1
    Molecular Formula:
    C46H69N7O15
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    White or off-white lyophilized solid
    Purity:
    95% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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  • Zerumbone | Enhances apoptosis

    CAS:
    471-05-6
    Catalog Number:
    10-2247
    Activity:
    Enhances apoptosis
    Chemical Name:
    (2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
    Molecular Weight:
    218.34
    Molecular Formula:
    C15H22O
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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