FGF
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Dovitinib | Multi-kinase inhibitor
From $75.00CAS:405169-16-6Catalog Number:10-2129Activity:Kinase inhibitorAlternate Names:TKI-258, CHIR258Chemical Name:4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-oneMolecular Weight:392.43Molecular Formula:C21H21FN6OSolubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Yellow-green solidPurity:99% by TLC
99% by HPLCStorage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Nintedanib | VEGFR, PDGFR, and FGFR kinase inhibitor
From $45.00Nintedanib (656247-17-5) is a potent inhibitor of VEGFR, PDGFR, FGFR (IC50 = 13-34 nM for VEGFR, 59-65 nM for PDGFR and 37-108 nM for FGFR subtypes).1 Also […]
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NVP-BGJ398 | Pan-specific FGFR inhibitor
From $65.00CAS:872511-34-7Catalog Number:10-4817Activity:Pan-specific FGFR inhibitorChemical Name:3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-{[4-(4-ethyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)-1-methylureaAlternate Names:InfigratinibMolecular Weight:560.48Molecular Formula:C26H31Cl2N7O3Solubility:Soluble in DMSO (up to 5 mg/ml)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
Pazopanib | Multi-receptor tyrosine kinase inhibitor
From $40.00Pazopanib (444731-52-6) inhibits multiple receptor tyrosine kinases including VEGFR1,2 and 3 (IC50s=10, 30, 47 nM respectively) and PDGFRα, β and c-Kit (IC50s=71, 84, 74 nM respectively) […]
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PD173074 | FGFR inhibitor
From $35.00CAS:219580-11-7Catalog Number:10-4505Activity:FGFR inhibitorChemical Name:1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)ureaMolecular Weight:523.67Molecular Formula:C28H41N7O3Solubility:Soluble in DMSO.Physical Properties:Yellow solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT
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