ER Stress

  • 4µ8C | IRE1 ribonuclease inhibitor

    CAS:
    14003-96-4
    Catalog Number:
    10-1579
    Activity:
    IRE1 ribonuclease inhibitor
    Chemical Name:
    7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran-8-carboxaldehyde
    Molecular Weight:
    204.18
    Molecular Formula:
    C11H8O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $32.00
  • AA147 | ATF6 activator

    CAS:
    393121-74-9
    Catalog Number:
    10-3973
    Activity:
    Activator of ER stress sensing protein ATF6
    Chemical Names:
    N-(2-Hydroxy-5-methylphenyl)-3-phenylpropanamide; Compound 147
    Molecular Weight:
    255.32
    Molecular Formula:
    C16H17NO2
    Solubility:
    Soluble in DMSO (>25 mg/ml); ethanol (>25 mg/mL)
    Physical Properties:
    Beige to pale orange solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • Azoramide | UPR modulator

    CAS:
    932986-18-0
    Catalog Number:
    10-4629
    Activity:
    UPR modulator
    Chemical Name:
    N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide
    Molecular Weight:
    308.83
    Molecular Formula:
    C15H17ClN2OS
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • C-DIM 8 | Nur77 Antagonist

    CAS:
    151358-47-3
    Catalog Number:
    10-5157
    Activity:
    Nur77 antagonist
    Chemical Names:
    1,1-Bis(3’-indolyl)-1-(p-hydroxyphenyl)methane
    Alternate Name:
    DIM-C-pPhOH
    Molecular Weight:
    338.41
    Molecular Formula:
    C23H18N2O
    Solubility:
    Soluble in DMSO (35 mg/ml); ethanol (35 mg/ml)
    Physical Properties:
    Pink solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $40.00
  • Ceapin-A7 | ATF6α/UPR inhibitor

    CAS:
    2323027-38-7
    Catalog Number:
    10-3974
    Activity:
    ATF6α/UPR inhibitor
    Chemical Names:
    N-(1-{[2,4-bis(Trifluoromethyl)phenyl]methyl}-1H-pyrazol-4-yl)-5-(furan-2-yl)-1,2-oxazole-3-carboxamide
    Molecular Weight:
    470.33
    Molecular Formula:
    C20H12F6N4O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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