DNA Damage Response

  • 2′-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor

    CAS:
    10356-76-0
    Catalog Number:
    10-2685
    Activity:
    Irreversible DNA methyl transferase inhibitor
    Alternate Names:
    FCDR; NSC-48006; FdCyd
    Chemical Name:
    5-Fluoro-2’deoxycytidine
    Molecular Weight:
    245.21
    Molecular Formula:
    C9H12FN3O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • 5-Azacytidine | DNA hypomethylation agent

    CAS:
    320-67-2
    Catalog Number:
    10-1267
    Activity:
    DNA hypomethylation agent
    Alternate Names:
    Ladakamycin; U-18496; NSC-102816; AzaC
    Chemical Name:
    4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
    Molecular Weight:
    244.21
    Molecular Formula:
    C8H12N4O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
  • 8-Oxo-2′-deoxyguanosine | Marker for DNA damage

    CAS:
    88847-89-6
    Catalog Number:
    10-2690
    Activity:
    Marker for DNA damage
    Alternate Names:
    8-Oxo-dG; Oxo-dG
    Chemical Name:
    8-Oxo-7,8-dihydro-2′-deoxyguanosine
    Molecular Weight:
    283.25
    Molecular Formula:
    C10H13N5O5
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $38.00
  • A-196 | SUV420H1/H2 methyltransferase inhibitor

    CAS:
    1982372-88-2
    Catalog Number:
    10-4018
    Activity:
    SUV420H1/H2 methyltransferase inhibitor
    Chemical Name:
    Cyclopentyl-(6,7-dichloro-4-pyridin-4-yl-phthalazin-1-yl)-amine
    Molecular Weight:
    359.25
    Molecular Formula:
    C18H16Cl2N4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $70.00
  • Adavosertib | Wee1 kinase inhibitor

    CAS:
    955365-80-7
    Catalog Number:
    10-4823
    Activity:
    Wee1 kinase inhibitor
    Chemical Names:
    1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)-phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one
    Alternate Name:
    MK-1775; AZD1775
    Molecular Weight:
    500.61
    Molecular Formula:
    C27H32N8O2
    Solubility:
    Soluble in DMSO (70 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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