ER Stress

  • Deoxymannojirimycin HCl | Mannosidase inhibitor

    CAS:
    73465-43-7
    Catalog Number:
    10-2798
    Activity:
    Mannosidase inhibitor
    Chemical Name:
    2R-(Hydroxymethyl)-3R,4R,5R-piperidinetriol hydrochloride
    Alternate Names:
    1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride
    Molecular Weight:
    199.63
    Molecular Formula:
    C6H13NO4 • HCl
    Solubility:
    Soluble in Water (up to 5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $40.00
  • Erastin | Ferroptosis inducer

    CAS:
    571203-78-6
    Catalog Number:
    10-3406
    Activity:
    Ferroptosis inducer
    Chemical Name:
    2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
    Molecular Weight:
    547.04
    Molecular Formula:
    C30H34ClN4O4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
  • ISRIB | Integrated stress response inhibitor

    CAS:
    159403-47-8
    Catalog Number:
    10-1539
    Activity:
    Integrated stress response inhibitor
    Chemical Name:
    N.N’-trans-1,4-Cyclohexanediylbis[2-(4-chlorophenoxy)acetamide
    Alternate Names:
    trans-ISRIB
    Molecular Weight:
    451.34
    Molecular Formula:
    C22H24Cl2N2O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • ML241 | p97 AAA ATPase inhibitor

    CAS:
    1346528-06-0
    Catalog Number:
    10-1555
    Activity:
    p97 AAA ATPase inhibitor
    Chemical Name:
    N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine
    Alternate Name:
    CID49830260
    Molecular Weight:
    372.46
    Molecular Formula:
    C23H24N4O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $90.00
  • Monocrotaline | Induces pulmonary fibrosis

    CAS:
    315-22-0
    Catalog Number:
    10-2872
    Activity:
    Induces pulmonary fibrosis
    Chemical Name:
    (3R,4R,5R)-4,5,8,10,12,13,13aR,13bR-Octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione
    Alternate Names:
    Crotaline; MCT; NSC28693
    Molecular Weight:
    325.36
    Molecular Formula:
    C16H23NO6
    Solubility:
    Soluble in DMSO (up to 50 mg/ml with warming), in Ethanol (up to 10 mg/ml with warming) or in organic solvents such as Chloroform (up to 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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