mTOR

  • Everolimus | mTOR inhibitor

    CAS:
    159351-69-6
    Catalog Number:
    10-2136
    Activity:
    mTOR inhibitor
    Alternate Names:
    SDZ RAD; RAD001
    Chemical Name:
    40-O-(2-Hydroxyethyl)rapamycin
    Molecular Weight:
    958.25
    Molecular Formula:
    C53H84NO14
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $55.00
  • INK-128 | TORC1/2 inhibitor

    CAS:
    1224844-38-5
    Catalog Number:
    10-3362
    Activity:
    TORC1/2 inhibitor
    Chemical Name:
    3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    Alternate Names:
    MLN-0128
    Molecular Weight:
    309.33
    Molecular Formula:
    C15H15N7O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Metformin HCl | Anti-diabetic agent

    CAS:
    1115-70-4
    Catalog Number:
    10-2469
    Activity:
    Anti-diabetic agent
    Chemical Name:
    1,1-Dimethylbiguanide hydrochloride
    Molecular Weight:
    165.63
    Molecular Formula:
    C4H11N5 HCl
    Solubility:
    Soluble in DMSO (up to 8 mg/ml) or in Water (up to 16 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $30.00
  • Niclosamide | STAT3 signaling inhibitor

    CAS:
    50-65-7
    Catalog Number:
    10-2474
    Activity:
    STAT3 signaling inhibitor
    Chemical Name:
    5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
    Molecular Weight:
    327.13
    Molecular Formula:
    C13H8Cl2N2O4
    Solubility:
    Soluble in DMSO (up to 3 mg/ml), or in Ethanol (up to 6 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $28.00
  • NVP-BEZ235 | PI3-K and mTOR inhibitor

    CAS:
    915019-65-7
    Catalog Number:
    10-2153
    Activity:
    PI 3-K and mTOR inhibitor
    Chemical Name:
    2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
    Molecular Weight:
    469.55
    Molecular Formula:
    C30H23N5O
    Solubility:
    Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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