my account
Login
  Loading... Please wait...

Product Details

17-DMAG | HSP90 inhibitor

17-DMAG (150270-08-9) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and induces apoptosis in a variety of tumor cell lines. Inhibits angiogenesis. Cell Permeable.

References/Citations
1) Glaze et al. (2005), Preclinical toxicity of geldanamycin analog 17-(dimethylaminoethylamino)-demthoxygeldanamycin (17-DMAG) in rats and dogs; potential clinical relevance; Cancer Chemother. Pharmacol., 56 637
2) Kaur et al. (2004), Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demthoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator; Clin. Cancer Res., 10 4813

swipe
17-DMAG | 150270-08-9 | Structure | Supplier

Catalog#  10-1169

$50.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
150270-08-9
Catalog Number:
10-1169
Activity:
HSP90 inhibitor
Alternate Names:
NSC 707545
Chemical Name:
17-[2-(Dimethylamino)ethyl]amino-17-desmethoxygeldanamycin
Molecular Weight:
616.763
Molecular Formula:
C32H48N4O8
Solubility:
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 10 mg/ml).
Physical Properties:
Purple solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the 17-DMAG | HSP90 inhibitor to your wish list.