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AEBSF HCl | Protease inhibitor

AEBSF HCl (CAS 30827-99-7) is an irreversible inhibitor of serine proteases including trypsin, chymotrypsin, plasmin, plasma kallikrein and thrombin. Stable, non-toxic and water-soluble alternative to PMSF.1 Typical working concentrations are 0.1-1 mg/ml. May be used in cell culture or in cell lysis buffers.  Inhibits NADPH oxidase activation.2

References/Citations

1) Powers et al. (2002), Irreversible inhibitors of serine, cysteine and threonine proteases; Chem. Rev., 102 4639
2) Diatchuk et al. (1997), Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds; J. Biol. Chem., 272 13292

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Focus Biomolecules cell signaling reagent supplier, chemical structure of AEBSF HCl | Protease inhibitor | CAS 30827-99-7

Catalog#  10-1348-0050

$38.00
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CAS:
30827-99-7
Catalog Number:
10-1348
Activity:
Protease inhibitor
Chemical Name:
4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
Molecular Weight:
239.69
Molecular Formula:
C8H10FNO2S • HCl
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Water (up to 100 mg/ml)
Physical Properties:
White solid
Purity:
98%
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions at pH <7 are stable for up to 6 months if stored in the refrigerator
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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