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Product Details

ALLM | Calpain inhibitor

ALLM (136632-32-1) is a cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM).1 Weak inhibitor of the chymotrypsin-like activity of the proteasome.2 Cell permeable.

References/Citations

1) Sasaki et al. (1990), Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins; J. Enzyme Inhib., 3 195
2) Vinitsky et al. (1992), Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex; Biochemistry, 31 9421

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ALLM | 136632-32-1 | Structure | Supplier

Catalog#  10-1349-0005

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
136632-32-1
Catalog Number:
10-1349
Activity:
Calpain inhibitor
Chemical Name:
N-Acetyl-Leu-Leu-Methional
Alternate Names:
Ac-LLM-CHO
Molecular Weight:
401.56
Molecular Formula:
C19H35N3O4S
Solubility:
Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
98% by HPLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

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