my account
Login
  Loading... Please wait...

Product Details

BAPTA-AM | cellular calcium sponge

BAPTA-AM (126150-97-8) is a selective cell permeable Ca2+ chelator. It is a widely used intracellular calcium sponge1,2. Rapidly taken up by cells where it is irreversibly hydrolyzed to BAPTA by intracellular esterases. Pretreatment of cells with BAPTA-AM inhibits thapsigargin-induced responses3.

References/Citations
1) Smith et al. (1992), Cytosolic calcium as a second messanger for collagen-induced platelet responses; Biochem. J., 288 925
2) Yoshida et al. (1993), Role of calcium ion in induction of apoptosis by etoposide in human leukemia HL-60 cells; Biochem. Biophys. Res. Commun., 196 927
3) Jiang et al. (1994), Intracellular Ca2+ signals activate apoptosis in thymocytes: studies using the Ca(2+)-ATPase inhibitor thapsigargin; Exp. Cell Res., 212 84

swipe
BAPTA-AM | 126150-97-8 | Structure | Supplier

Catalog#  10-1203

$50.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
Request Bulk Quote
CAS:
126150-97-8
Catalog Number:
10-1203
Activity:
cellular calcium sponge
Chemical Name:
1,2-bis-(2-Aminophenoxy)ethane-N,N,N',N'-tetraacetic acid, tetraacetoxymethyl ester
Molecular Weight:
764.7
Molecular Formula:
C34H40N2O18
Solubility:
Soluble in DMSO (up to 15 mg/ml), in DMF (up to 25 mg/ml) or in Ethanol (up to 5 mg/ml).
Physical Properties:
White solid
Purity:
95% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year as pplied. Solutions in DMSO, DMF or ethanol may be stored at -20°C for up to 1 week.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

Focus BiomoleculesPlymouth Meeting, PA USA1-855-FOCUS21

Connect with Focus

Click the button below to add the BAPTA-AM | cellular calcium sponge to your wish list.