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BML-259 | CDK5/p25 inhibitor

CAS:
267654-00-2
Catalog Number:
10-1025
Activity:
CDK5/p25 inhibitor
Chemical Name:
N-(5-isopropyl-thiazol-2-yl)phenylacetamide
Molecular Weight:
260.36
Molecular Formula:
C14H16N2OS
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
white solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

BML-259 (267654-00-2) is a potent inhibitor of Cdk5/p25 (IC50 = 64 nM) and Cdk2 (IC50 = 98nM).1

References/Citations:

1) Helal et al. (2004) Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease; Bioorg. Med. Chem. Lett. 14 5521

BML-259 | CDK5/p25 inhibitor is also available in the Cellular Metabolism Library.
CAS:
267654-00-2
Catalog Number:
10-1025
Activity:
CDK5/p25 inhibitor
Chemical Name:
N-(5-isopropyl-thiazol-2-yl)phenylacetamide
Molecular Weight:
260.36
Molecular Formula:
C14H16N2OS
Solubility:
Soluble in DMSO (up to 25 mg/ml).
Physical Properties:
white solid
Purity:
98% by TLC
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT

Safety Data Sheet:

N/A

Product Data Sheet:

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