Mitochondrial
Showing 1–12 of 13 results
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Cellular Metabolism
A77 1726 | DHODH inhibitor
Rated 0 out of 5A77 1726 (108605-62-5) is a pyrimidine biosynthesis inhibitor and immunomodulator.1 Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH)...$45.00 – $150.00 Select options -
Cancer
AGI-5198 | R132 mutant isocitrate dehydrogenase inhibitor
Rated 0 out of 5AGI-5198 (135526-35-0) is a potent (IC50 = 70 nM) inhibitor of mutant isocitrate dehydrogenase 1(IDH1).1 It is selective for the R132H-IDH1 mutant...$70.00 – $225.00 Select options -
New Products
Brequinar sodium | Dihydroorotate dehydrogenase inhibitor, antiviral
Rated 0 out of 5Brequinar sodium (96201-88-6) is an inhibitor of dihydroorotate dehydrogenase (DHODH)1,2 with IC50’s between 0.2 and 5.8 µM in various cell lines3 ...$70.00 – $275.00 Select options -
Cancer
CPI-613 | KGDH and PDH inhibitor
Rated 0 out of 5CPI-613 (95809-78-2) is a lipoic acid analog which potently disrupts mitochondrial metabolism with selectivity for tumor cells in vitro and shows s...$50.00 – $200.00 Select options -
Apoptosis
FCCP | Inhibits mitochondrial oxidative phosphorylation
Rated 0 out of 5FCCP (370-86-5) is an extremely potent uncoupler of mitochondrial oxidative phosphorylation (IC50 = 20 nM).1 Induces apoptosis in a variety of cell...$58.00 – $228.00 Select options -
Cellular Metabolism
HQNO | NADH oxidase inhibitor
Rated 0 out of 5HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial ...$85.00 – $340.00 Select options -
Cellular Metabolism
iGP-1 | Mitochondrial GPDH inhibitor
Rated 0 out of 5iGP-1 (27031-00-1) is a potent and cell permeable inhibitor of mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 μM, that is selec...$50.00 – $180.00 Select options -
Approved Drugs
Leflunomide | Immunosuppressant
Rated 0 out of 5Leflunomide (75706-12-6) pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug)1. Displays immunomodulatory activity inhibi...$40.00 – $160.00 Select options -
Apoptosis
Lonidamine | Inhibits Cancer Cell Metabolism
Rated 0 out of 5Lonidamine (50264-69-2) was originally investigated as an antispermatogenic agent.1 Lonidamine has been shown to decrease oxygen consumption as wel...$45.00 – $175.00 Select options -
AMPK
Metformin HCl | Anti-diabetic agent
Rated 0 out of 5Metformin HCl (1115-70-4) is a clinically useful antidiabetic agent. Lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepati...$30.00 – $120.00 Select options -
Bioactive Lipids
N-Oleoylphenylalanine | Endogenous Uncoupler of Mitochondrial Respiration
Rated 0 out of 5N-Oleoylphenylalanine is an endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylala...$50.00 – $200.00 Select options -
ATPase
Oligomycin Complex | Mitochondrial ATPase inhibitor
Rated 0 out of 5Oligomycin (1404-19-9) inhibits mitochondrial F1F0 ATP synthase.1 A useful tool for decreasing cellular ATP levels.2 Induces autophagy.3 Stimulates...$57.00 – $228.00 Select options
Cellular Metabolism Mitochondrial