my account
Login
  Loading... Please wait...

Mitochondrial

Sort by
  • A77 1726 | 108605-62-5 | Structure | supplier
    A77 1726 | DHODH inhibitor
    $45.00
    A77 1726 (108605-62-5) is a pyrimidine biosynthesis inhibitor and immunomodulator.1 Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH).2 Leflunomide (Cat.# 10-2369) is rapidly metabolized in human hepatocytes to...

    Choose Options
  • AGI-5198 | R132 mutant isocitrate dehydrogenase inhibitor
    AGI-5198 | R132 mutant isocitrate dehydrogenase inhibitor
    $70.00
    AGI-5198 (135526-35-0) is a potent (IC50 = 70 nM) inhibitor of mutant isocitrate dehydrogenase 1(IDH1).1  It is selective for the R132H-IDH1 mutant and does not affect wild type cells.2  This mutation results in...

    Choose Options
  • FCCP | 370-86-5 | Structure | Supplier
    FCCP | Inhibits mitochondrial oxidative phosphorylation
    $58.00
    FCCP (370-86-5) is an extremely potent uncoupler of mitochondrial oxidative phosphorylation (IC50 = 20 nM).1 Induces apoptosis in a variety of cell lines.2 Inhibits wild type and mutant beta-amyloid production in embryonic...

    Choose Options
  • HQNO | 341-88-8 | Structure | Supplier
    HQNO | NADH oxidase inhibitor
    $85.00
    HQNO (341-88-8) is a naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein. HQNO inhibits NADH oxidase (NADH) and Na+-dependent...

    Choose Options
  • Leflunomide | Immunosuppressant
    Leflunomide | Immunosuppressant
    $40.00
    Leflunomide (75706-12-6) pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug)1. Displays immunomodulatory activity inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH)2; however...

    Choose Options
  • Lonidamine | Inhibits Cancer Cell Metabolism
    Lonidamine | Inhibits Cancer Cell Metabolism
    $45.00
    Lonidamine (50264-69-2) was originally investigated as an antispermatogenic agent.1 Lonidamine has been shown to decrease oxygen consumption as well as aerobic and anaerobic glycolysis in tumor cells leading to apoptosis.2...

    Choose Options
  • Metformin HCl | Anti-diabetic agent
    Metformin HCl | Anti-diabetic agent
    $30.00
    Metformin HCl (1115-70-4) is a clinically useful antidiabetic agent. Lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis by activation of the AMP-activated protein kinase (AMPK)...

    Choose Options
  • N-Oleoylphenylalanine | Structure | Supplier
    N-Oleoylphenylalanine | Endogenous Uncoupler of Mitochondrial Respiration
    $50.00
    N-Oleoylphenylalanine is an endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylalanine binds directly to mitochondria and functions as an endogenous uncoupler...

    Choose Options
  • Oligomycin Complex | Mitochondrial ATPase inhibitor
    Oligomycin Complex | Mitochondrial ATPase inhibitor
    $55.00
    Oligomycin (1404-19-9) inhibits mitochondrial F1F0 ATP synthase.1 A useful tool for decreasing cellular ATP levels.2 Induces autophagy.3 Stimulates lysosome acidification.4 Oligomycin protects against ischemic kidney in male...

    Choose Options
  • TTFA | Mitochondrial Complex II inhibitor
    TTFA | Mitochondrial Complex II inhibitor
    $25.00
    TTFA (326-91-0) blocks the respiratory chain complex II causing inhibition of mitochondrial respiration.  Respiratory chain complex II inhibition is caused via binding of TTFA to two ubiquinone binding sites, Qp...

    Choose Options

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Connect with Focus