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Product Details

Deferiprone | Iron Chelator

Deferiprone (30652-11-0) is a clinically useful iron chelator.1 It attenuated blood-brain-barrier breakdown and brain mitochondrial dysfunction in rats with chronic iron-overload.2 Iron chelation therapy has been suggested as a possible therapy for Alzheimers Disease.3

References/Citations
1) Hider and Hoffbrand (2018), The Role of Deferiprone in Iron Chelation; N. Engl. J. Med., 379 2140
2) Sripetchwandee et al. (2016), A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloid-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload., Neuroscience 332 191
3) Liu et al. (2018), Iron and Alzheimer’s Disease: From Pathogenesis to Therapeutic Implications; Front. Neurosci, 12 632

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Catalog#  10-4950-0500

$20.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
30652-11-0
Catalog Number:
10-4950
Activity:
Iron chelator
Chemical Name:
3-Hydroxy-1,2-dimethylpyrid-4-one
Alternate Name:
Ferriprox
Molecular Weight:
139.15
Molecular Formula:
C7H9NO2
Solubility:
Soluble in Water (up to 5 mg/ml with warming).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20° (des.)
Stability:
Stable for 1 year as supplied. Solutions are not stable and must be prepared fresh daily.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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