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Product Details

Everolimus | mTOR inhibitor

Everolimus (159351-69-6) is a semisynthetic analog of rapamycin (Cat.# 10-1104) with potent immunosuppressive activity.1 Inhibits mTOR.2 Everolimus is a clinically useful immunosuppressant.3

References/Citations
1) Schuurman et al. (1997), SDZ RAD, a new rapamycin derivative: synergism with cyclosporine; Transplantation, 64 32
2) Neuhaus et al. (2001), mTOR inhibitors: an overview; Liver Transpl., 7 473
3) Kahan et al. (2002), Therapeutic drug monitoring of immunosuppressant drugs in clinical practice; Clin. Ther., 24 330

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Focus Biomolecules cell signaling reagent supplier, chemical structure of Everolimus | mTOR inhibitor | CAS 159351-69-6

Catalog#  10-2136

$60.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
159351-69-6
Catalog Number:
10-2136
Activity:
mTOR inhibitor
Alternate Names:
SDZ RAD; RAD001
Chemical Name:
40-O-(2-Hydroxyethyl)rapamycin
Molecular Weight:
958.25
Molecular Formula:
C53H84NO14
Solubility:
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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