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Product Details

Lactacystin | Proteasome inhibitor

Lactacyctin (133343-34-7) is a specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Inhibition of the peptidyl-glutamyl peptide hydrolytic activity by lactacystin is relatively weak.

References/Citations
1) Omura et al. (1991), Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells; J. Antibiot., 44 113
2) Fenteany et al. (1995), Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin; Science, 268 726

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Focus Biomolecules cell signaling reagent supplier, structure of Lactacystin | Proteasome inhibitor | CAS 133343-34-7

Catalog#  10-1314

$126.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
133343-34-7
Catalog Number:
10-1314
Activity:
Proteasome inhibitor
Chemical Name:
Fermentation product from Streptomyces lactacystinaeus
Molecular Weight:
376.37
Molecular Formula:
C15H24N2O7
Solubility:
Soluble in DMSO (up to 20 mg/ml), in Water (up to 10 mg/ml), or in Ethanol (up to 1 mg/ml).
Physical Properties:
White solid - lyophilized
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° fo you to 1 month. Solutions in water are not stable and must be used with one working day. Aqueous solutions should not be stored.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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