N-Acetyl Puromycin (22852-13-7) down regulates SnoN and Ski protein expression. Induces TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.
1) Hernandez-Damian et al. (2013), Downregulation of SnoN oncoprotein induced by antibiotics anisomycin and puromycin positively regulates transforming growth factor-β signals; Biochim. Biophys. Acta, 1830 5049