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N-Acetyl Puromycin | Down regulates SnoN and Ski expression

N-Acetyl Puromycin (22852-13-7) down regulates SnoN and Ski protein expression. Induces TGF-β signaling, independently of MAPK activation. Does not bind ribosomes or block protein synthesis.

References/Citations

1) Hernandez-Damian et al. (2013), Downregulation of SnoN oncoprotein induced by antibiotics anisomycin and puromycin positively regulates transforming growth factor-β signals; Biochim. Biophys. Acta, 1830 5049

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Focus Biomolecules supplier, chemical structure N-Acetyl Puromycin | Down regulates SnoN & Ski expression | CAS 22852-13-7

Catalog#  10-1591-0005

$65.00
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CAS:
22852-13-7
Catalog Number:
10-1591
Activity:
Down regulates SnoN and Ski expression
Chemical Name:
3’-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3’-deoxy-N,N-dimethyladenosine
Molecular Weight:
513.55
Molecular Formula:
C24H31N7O6
Solubility:
Soluble in DMSO (up to 70 mg/ml) or in DMF (up to 55 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 1 year as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
Shipping Code:
RT
FeaturedDescription:
Induces TGF-β signaling, independently of MAPK activation
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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