A team headed by distinguished neuroscientist Alcino Silva recently showed that expression of C-C chemokine receptor type 5 (CCR5) expression reduced memory recall, and maraviroc (Focus
Perylenequinones are a family of structurally novel fungal or plant natural products which act as photosensitizers. They absorb light energy, enabling them to generate reactive oxygen
In Nature Communications, Zhang et al. show that DJ001, a selective allosteric inhibitor of protein tyrosine phosphatase sigma (PTPσ), promotes hematopoietic stem cell (HSC) regeneration. Treatment
In a fascinating paper just out in Cell Metabolism, Mathias Wenes and coworkers found that the mitochondrial pyruvate carrier (MPC) regulates memory T cell differentiation and
CHIR-99021 is another popular tool for stem cell maintenance which increases cell survival and proliferation. It is a GSK3β inhibitor, and Komiya et al. used CHIR-99021
The compound Y-27632 inhibits ROCK family kinases and is a very popular tool for embryonic stem cell (ESC) maintenance because it enhances survival and proliferation in
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