Beauvericin, a mycotoxin produced by various Fusarium spp, is an important food and animal feed contaminant. Its diverse toxic activities coupled with its ability to cross
An interesting review has just been published in the May 23 issue of Cell by A Suomalainen and J Nunnari entitled “Mitochondria at the Crossroads of
In a paper just out in Nature Aging, Goro Katsuumi and coworkers in Tokyo demonstrated that inhibition of sodium-glucose co-transporter 2 (SGLT2) with canagliflozin enhanced clearance
Last week the FDA approved Italfarmaco’s givinostat (ITF2357) for Duchenne muscular dystrophy. Givinostat is a novel histone deacetylase (HDAC) inhibitor and was approved for DMD patients
Focus Biomolecules will be exhibiting at the annual meeting of American Association for Cancer Research (AACR) in San Diego, April 7 – 10. Stop by our
New DUB inhibitor: Deubiquitinating enzymes, or DUBs, are proteases that regulate ubiquitination dynamics. DUBs have become promising targets for drug discovery across diverse therapeutic areas. For
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