Resorcylic acid lactones are a diverse family of fungal natural products which possess a variety of useful pharmacological activities. For example: Radicicol Hypothemycin and others are
Apoptolidin is a novel microbial natural product isolated from Nocardiopsis sp. It was shown to be a powerful inducer of apoptosis in a variety of cancer
In a recent paper in Nature, Bryan Roth et al. revealed detailed features in the recognition of DREADD actuators by designer receptors. Muscarinic DREADDs or designer
Urolithin A is a microbial metabolite of dietary ellagitannins produced in the gut. It has been shown to induce mitophagy and prolong lifespan in C. elegans
Focus will be exhibiting at ASCB Cell Biology, Dec 3-7 in Washington DC. Stop by our booth #2205 and chat with our scientists! Learn about our
Filipin III is a microbial natural product isolated from Streptomyces filipinensis. It is an important fluorescent probe for cellular cholesterol detection. In addition, because it binds
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