AM-404 | Anandamide transport inhibitor

CAS:
198022-70-7
Catalog Number:
10-2008
Activity:
Anandamide transport inhibitor
Chemical Name:
N-(4-Hydroxyphenyl)arachidonamide
Molecular Weight:
395.58
Molecular Formula:
C26H37NO2
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Compound is subject to oxidation, store under inert gas to protect from exposure to air. Solutions in DMSO or ethanol may be stored under nitrogen or argon at -20° for up to 3 months.
Shipping Code:
Blue Ice

Available Options

size :PriceQuantity 
10 mg$40.00
50 mg$160.00

AM-404 (198022-70-7) inhibits anandamide transport (IC50 = 1 μM) without inhibiting anandamide amidase or activating cannabinoid receptors.1,2 Vanilloid receptors are activated by AM-404.3 Active in vivo.1

References/Citations:

1) Calignano et al. (1997), Potentiation of anandamide hypotension by the transport inhibitor AM404; Eur. J. Pharmacol., 337 R1
2) Beltramo et al. (1997), Functional role of high-affinity anandamide transport, as revealed by selective inhibition; Science, 277 1094
3) Zygmunt et al. (2000), The anandamide inhibitor AM404 activates vanilloid receptors: Eur. J. Pharmacol. 396 39

CAS:
198022-70-7
Catalog Number:
10-2008
Activity:
Anandamide transport inhibitor
Chemical Name:
N-(4-Hydroxyphenyl)arachidonamide
Molecular Weight:
395.58
Molecular Formula:
C26H37NO2
Solubility:
Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml)
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°
Stability:
Stable for 1 year from date of purchase as supplied. Compound is subject to oxidation, store under inert gas to protect from exposure to air. Solutions in DMSO or ethanol may be stored under nitrogen or argon at -20° for up to 3 months.
Shipping Code:
Blue Ice

Safety Data Sheet:

N/A

Product Data Sheet:

Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee