Aging and Longevity

Prolonging quality lifespan has long been a goal of mankind. Ageing is an intrinsically complex process that depends on the interplay of random damage-driven mechanisms of ageing and genetically specific signaling pathways that influence longevity. Recent research has focused on many areas critical to the ageing process and longevity including epigenetics, stem cells, cellular senescence, ubiquitin/proteasome, inflammation, DNA damage and repair, mitochondrial function, and cellular stress

  • Metolazone | UPR activator and longevity inducer

    CAS:
    17560-51-9
    Catalog Number:
    10-5417
    Activity:
    UPR activator and longevity inducer
    Chemical Name:

    7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide

    Molecular Weight:
    365.83
    Molecular Formula:
    C16H16ClN3O3S
    Solubility:
    Soluble in DMSO (up to 36 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored desiccated at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • Oleoylethanolamide | GPR119 agonist / stimulates lipolysis

    CAS:
    111-58-0
    Catalog Number:
    10-1475
    Activity:
    GPR119 agonist: Stimulates lipolysis
    Chemical Name:
    N-(2-Hydroxyethyl)-9Z-octadecenamide
    Alternate Names:
    OEA
    Molecular Weight:
    325.53
    Molecular Formula:
    C20H39NO2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 35 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • OSS-128167 | SIRT6 Inhibitor

    CAS:
    887686-02-4
    Catalog Number:
    10-5197
    Activity:
    SIRT6 inhibitor
    Chemical Names:
    5-(3-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid
    Molecular Weight:
    366.33
    Molecular Formula:
    C19H14N2O6
    Solubility:
    Soluble in DMSO (25 mg/ml); Ethanol (25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $65.00
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  • Phenylacetyl-L-glutamine | Bioactive gut microbial metabolite

    CAS:
    28047-15-6
    Catalog Number:
    10-5706
    Activity:
    Bioactive gut microbial metabolite
    Chemical Names:
    (S)-5-Amino-5-oxo-2-(2-phenylacetamido)pentanoic acid
    Alternate Name:
    N-Phenylacetylglutamine, Phenylacetylglutamine;
    PhenylAc-Gln-OH; NSC-203800; PAG
    Molecular Weight:
    264.28
    Molecular Formula:
    C13H16N2O4
    Solubility:
    Soluble in DMSO (45 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $48.00
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  • Probucol supplier | CAS 23288-49-5 | Focus Biomolecules

    Probucol | Antioxidant hypercholesterolemic agent

    CAS:
    23288-49-5
    Catalog Number:
    10-2679
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  • Remodelin | Acetyltransferase NAT10 inhibitor

    CAS:
    949912-58-7
    Catalog Number:
    10-5085
    Activity:
    Acetyl-transferase NAT10 inhibitor
    Chemical Name:
    4-[2-(2-Cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile
    Molecular Weight:
    282.36
    Molecular Formula:
    C15H14N4S
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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