Prostratin | Promotes neuro-regeneration
NMR (Conforms)
Available Options
| Size : | Price | Quantity | |
|---|---|---|---|
| 1 mg | $110.00 | ||
| 5 mg | $500.00 |
Prostratin (60857-08-1) is a terpenoid, non-tumorigenic PKC activator isolated from Pimelia prostrata.1,2 Induces differentiation of human myeloid leukemia cells and potentiates differentiation by chemotherapeutic agents.3 Induces reactivation of latent HIV.4 Exerts a proliferative effect on neural progenitor cells in vitro and in vivo.5
References/Citations:
1) Cashmore et al. (1976), The structure of prostratin: a toxic tetracyclic diterpene ester from Pimelea Prostrata; Tetrahedron Lett., 17 1737
2) Miana et al. (2015), Prostratin: An Overview; Mini Rev. Med. Chem., 15 1122
3) Shen et al. (2015), The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents; Cancer Lett., 356 (2 Pt. B) 686
4) Biancotto et al. (2004), Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue; J. Virol., 78 10507
5) Geribaldi-Doldan et al. (2015), 12-Deoxyphorbols Promote Adult Neurogenesis by Inducing Neural Progenitor Cell Proliferation via PKC activation ; Int. J, Neuropsychopharmacol., 19 pyv085
NMR (Conforms)
Safety Data Sheet:
Product Data Sheet:
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Prostratin (60857-08-1) is a terpenoid, non-tumorigenic PKC activator isolated from Pimelia prostrata.1,2 Induces differentiation of human myeloid leukemia cells and potentiates differentiation by chemotherapeutic agents.3 Induces reactivation of latent HIV.4 Exerts a proliferative effect on neural progenitor cells in vitro and in vivo.5
References/Citations:
1) Cashmore et al. (1976), The structure of prostratin: a toxic tetracyclic diterpene ester from Pimelea Prostrata; Tetrahedron Lett., 17 1737
2) Miana et al. (2015), Prostratin: An Overview; Mini Rev. Med. Chem., 15 1122
3) Shen et al. (2015), The protein kinase C agonist prostratin induces differentiation of human myeloid leukemia cells and enhances cellular differentiation by chemotherapeutic agents; Cancer Lett., 356 (2 Pt. B) 686
4) Biancotto et al. (2004), Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue; J. Virol., 78 10507
5) Geribaldi-Doldan et al. (2015), 12-Deoxyphorbols Promote Adult Neurogenesis by Inducing Neural Progenitor Cell Proliferation via PKC activation ; Int. J, Neuropsychopharmacol., 19 pyv085
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21
Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21
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