Cell Cycle Checkpoints
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Adavosertib | Wee1 kinase inhibitor
From $45.00CAS:955365-80-7Catalog Number:10-4823Activity:Wee1 kinase inhibitorChemical Names:1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)-phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-oneAlternate Name:MK-1775; AZD1775Molecular Weight:500.61Molecular Formula:C27H32N8O2Solubility:Soluble in DMSO (70 mg/ml)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
AZD7762 | Checkpoint kinase 1/2 inhibitor
From $60.00CAS:860352-01-8 (free base)Catalog Number:10-4771Activity:Checkpoint kinase 1/2 inhibitorChemical Name:3-(Carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide hydrochlorideMolecular Weight:398.88Molecular Formula:C17H19FN4O2S • HClSolubility:Soluble in DMSO (up to at least 25 mg/ml).Physical Properties:Yellow or brown solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
BML-277 | CHK2 inhibitor
From $60.00CAS:516480-79-8Catalog Number:10-1024Activity:CHK2 inhibitorChemical Name:2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamideMolecular Weight:363.81Molecular Formula:C20H14ClN3O2Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR conformsStorage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Cantharidin | Phosphatase PP2A inhibitor
From $40.00CAS:56-25-7Catalog Number:10-1013Activity:Phosphatase PP2A inhibitorChemical Name:3α,7α-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dioneMolecular Weight:196.2Molecular Formula:C10H12O4Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 weeks.Shipping Code:RT -
LY2603618 | Potent and selective Chk1 inhibitor
From $50.00CAS:911222-45-2Catalog Number:10-4123Activity:Potent and selective Chk1 inhibitorChemical Name:N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)ureaAlternate Names:RabusertibMolecular Weight:436.30Molecular Formula:C18H22BrN5O3Solubility:Soluble in DMSO (up to 10 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT
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