Histone Demethylation

  • (±) Tranylcypromine hemisulfate | Demethylase inhibitor

    CAS:
    13492-01-8
    Catalog Number:
    10-4535
    Activity:
    Demethylase inhibitor
    Chemical Name:
    trans-(±)-2-Phenylcyclopropylamine hemisulfate
    Molecular Weight:
    182.23
    Molecular Formula:
    C9H11N 1/2(H2SO4)
    Solubility:
    Soluble in Water (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
  • AS-8351 | KDM5B histone demethylase inhibitor

    CAS:
    796-42-9
    Catalog Number:
    10-1597
    Activity:
    KDM5B histone demethylase inhibitor
    Chemical Names:
    2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone
    Molecular Weight:
    291.30
    Molecular Formula:
    C17H13N3O2
    Solubility:
    Soluble in DMSO (45 mg/ml); ethanol (10 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • CPI-455 | Lysine demethylase KDM5 inhibitor

    CAS:
    1628208-23-0
    Catalog Number:
    10-4035
    Activity:
    Lysine demethylase KDM5 inhibitor
    Chemical Name:
    7-Oxo-5-phenyl-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
    Molecular Weight:
    278.32
    Molecular Formula:
    C16H14N4O
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $90.00
  • Daminozide | KDM2/7 demethylase inhibitor

    CAS:
    1596-84-5
    Catalog Number:
    10-1403
    Activity:
    KDM2/7 demethylase inhibitor
    Alternate Names:
    N-(Dimethylamino)succinamic acid
    Chemical Name:
    1-(2,2-Dimethylhydrazide)butanedioic acid
    Molecular Weight:
    160.17
    Molecular Formula:
    C6H12N2O3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 3 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
  • Deferasirox | Iron Chelator

    CAS:
    201530-41-8
    Catalog Number:
    10-4949
    Activity:
    Iron chelator
    Chemical Names:
    4-[3,5-bis(2-Hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid
    Alternate Name:
    ICL670
    Molecular Weight:
    373.36
    Molecular Formula:
    C21H15N3O4
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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