Cell Cycle / Cell Division

  • LDN-192960 2HCl | Haspin and DYRK2/3 inhibitor

    CAS:
    184582-62-5
    Catalog Number:
    10-4836
    Activity:
    Haspin and DYRJ2/3 inhibitor
    Chemical Names:
    3-(2,7-Dimethoxyacridin-9-yl)sulfanylpropan-1-amine dihydrochloride
    Molecular Weight:
    401.35
    Molecular Formula:
    C18H20N2O2S·2HCl
    Solubility:
    Soluble in DMSO (>25 mg/ml); Water (2 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $55.00
  • LY2603618 | Potent and selective Chk1 inhibitor

    CAS:
    911222-45-2
    Catalog Number:
    10-4123
    Activity:
    Potent and selective Chk1 inhibitor
    Chemical Name:
    N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)urea
    Alternate Names:
    Rabusertib
    Molecular Weight:
    436.30
    Molecular Formula:
    C18H22BrN5O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Palbociclib | CDK4/CDK6 inhibitor

    CAS:
    571190-30-2
    Catalog Number:
    10-4760
    Activity:
    CDK4/CDK6 inhibitor
    Chemical Name:
    6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-piperazin-1-yl)pyridine-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one
    Alternate Names:
    PD-332991
    Molecular Weight:
    447.53
    Molecular Formula:
    C24H29N7O2
    Solubility:
    Soluble in DMSO (up to 2 mg/ml with warming)
    Physical Properties:
    Yellow solid
    Purity:
    99% by HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • Purvalanol A | CDK inhibitor

    CAS:
    212844-53-6
    Catalog Number:
    10-2868
    Activity:
    CDK Inhibitor
    Chemical Name:
    (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol
    Alternate Names:
    NG-60
    Molecular Weight:
    388.89
    Molecular Formula:
    C19H25ClN6O
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    Pale green solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
  • Ribociclib | CDK4/6 inhibitor

    CAS:
    1211441-98-3
    Catalog Number:
    10-4807
    Activity:
    CDK4/6 inhibitor
    Chemical Name:
    7-Cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
    Alternate Names:
    LEE011
    Molecular Weight:
    434.54
    Molecular Formula:
    C23H30N8O3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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