Highly Selective Inhibitors
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Acalabrutinib | Highly selective BTK inhibitor
From $45.00CAS:1420477-60-6Catalog Number:10-4806Alternate Name:ACP-196Activity:Highly selective BTK inhibitorChemical Name:4-[8-Amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamideMolecular Weight:465.52Molecular Formula:C26H23N7O2Solubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Adavosertib | Wee1 kinase inhibitor
From $45.00CAS:955365-80-7Catalog Number:10-4823Activity:Wee1 kinase inhibitorChemical Names:1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)-phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-oneAlternate Name:MK-1775; AZD1775Molecular Weight:500.61Molecular Formula:C27H32N8O2Solubility:Soluble in DMSO (70 mg/ml)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Alectinib | Potent and selective ALK inhibitor
From $60.00CAS:1256580-46-7Catalog Number:10-4793Activity:Potent and selective ALK inhibitorChemical Name:9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrileAlternate Name:CH5424802Molecular Weight:482.62Molecular Formula:C30H34N4O2Solubility:Soluble in DMSO (up to 5 mg/ml with warming).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.Shipping Code:RT -
Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc
From $60.00CAS:1028486-01-2Catalog Number:10-4124Activity:Potent and selective inhibitor of Aurora A / Destabilizes MycChemical Name:4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acidAlternate Names:MLN8237Molecular Weight:518.92Molecular Formula:C27H20ClFN4O4Solubility:Soluble in DMSO (up to 5 mg/ml)Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
AZ20 | ATR kinase inhibitor
From $55.00CAS:1233339-22-4Catalog Number:10-4675Activity:ATR kinase inhibitorChemical Name:4-{4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl}-1H-indoleMolecular Weight:412.51Molecular Formula:C21H24N4O3SSolubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
