Immunoregulatory Archives | Page 3 of 5

GSK8612 | Highly selective TBK1 inhibitor

CAS:

2361659-62-1

Catalog Number:

10-4693

Activity:

Highly selective TBK1 inhibitor

Chemical Names:

4-[[[5-Bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide

Molecular Weight:

520.33

Molecular Formula:

C₁₇H₁₇BrF₃N₇O₂S

Solubility:

Soluble in DMSO (20 mg/ml)

Physical Properties:

Beige solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $65.00
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Ibrutinib | BTK inhibitor

CAS:

936563-96-1

Catalog Number:

10-4757

Alternate Name:

PCI-32765

Activity:

BTK inhibitor/Cancer immunotherapy enhancer

Chemical Name:

1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one

Molecular Weight:

440.51

Molecular Formula:

C₂₅H₂₄N₆O₂

Solubility:

Soluble in DMSO ( up to at least 25 mg/ml)

Physical Properties:

White or off-white solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $40.00
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Idelalisib | Selective PI3Kδ Inhibitor

CAS:

870281-82-6

Catalog Number:

10-4820

Activity:

Selective PI3Kδ Inhibitor

Chemical Name:

5-Fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one

Alternate Names:

CAL-101

Molecular Weight:

415.43

Molecular Formula:

C₂₁H₁₈FN₇O

Solubility:

Soluble in DMSO (>25 mg/ml)

Physical Properties:

White solid

Purity:

>98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $60.00
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IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

CAS:

1693758-51-8

Catalog Number:

10-4827

Activity:

Selective PI3K-gamma inhibitor / Immuno-oncology agent

Chemical Name:

(S)-2-Amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

Molecular Weight:

629.68

Molecular Formula:

C₃₀H₂₄N₈O₂

Solubility:

Soluble in DMSO (up to at least 25 mg/ml)

Physical Properties:

Pale yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
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IQ-1S | JNK3 inhibitor

CAS:

1421610-21-0

Catalog Number:

10-1513

Activity:

JNK3 inhibitor

Chemical Name:

11H-Indeno[1,2-b]quinoxaline-11-one oxime, sodium salt

Molecular Weight:

269.23

Molecular Formula:

C₁₅H₈N₃O • Na

Solubility:

Soluble in DMSO (up to 15 mg/ml)

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $40.00
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Immunoregulatory

GSK8612 | Highly selective TBK1 inhibitor

Ibrutinib | BTK inhibitor

Idelalisib | Selective PI3Kδ Inhibitor

IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

IQ-1S | JNK3 inhibitor

EXPLORE OTHER Kinases

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Immunoregulatory

GSK8612 | Highly selective TBK1 inhibitor

Ibrutinib | BTK inhibitor

Idelalisib | Selective PI3Kδ Inhibitor

IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

IQ-1S | JNK3 inhibitor

EXPLORE OTHER Kinases

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21