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mTOR

  • AZD8055 | mTOR kinase inhibitor

    CAS:
    1009298-09-2
    Catalog Number:
    10-4816
    Activity:
    mTOR kinase inhibitor
    Chemical Name:
    (5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol
    Molecular Weight:
    465.54
    Molecular Formula:
    C25H31N5O4
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • INK-128 | TORC1/2 inhibitor

    CAS:
    1224844-38-5
    Catalog Number:
    10-3362
    Activity:
    TORC1/2 inhibitor
    Chemical Name:
    3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
    Alternate Names:
    MLN-0128
    Molecular Weight:
    309.33
    Molecular Formula:
    C15H15N7O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC/HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • MHY1485 | mTOR activator

    CAS:
    326914-06-1
    Catalog Number:
    10-1604
    Activity:
    mTOR activator
    Chemical Name:
    4,6-Di-4-morpholinyl-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
    Molecular Weight:
    387.39
    Molecular Formula:
    C17H21N7O4
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in DMF (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • NVP-BEZ235 | PI3-K and mTOR inhibitor

    CAS:
    915019-65-7
    Catalog Number:
    10-2153
    Activity:
    PI 3-K and mTOR inhibitor
    Chemical Name:
    2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile
    Molecular Weight:
    469.55
    Molecular Formula:
    C30H23N5O
    Solubility:
    Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • PI-103 | Potent inhibitor of PI-3 kinase, mTOR, and DNA-PK

    CAS:
    371935-74-9
    Catalog Number:
    10-5406
    Activity:
    Potent inhibitor of PI-3 kinase, mTOR and DNA-PK
    Chemical Name:

    3-[4-(4-Morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol

    Molecular Weight:
    348.36
    Molecular Formula:
    C19H16N4O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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